Protein Molecular Weight Markers
ABclonal Technology ADGRA3 Rabbit pAb
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia.
ABclonal Technology GLYAT Rabbit pAb
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoAs. Two transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology CACNG1 Rabbit pAb
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
ABclonal Technology DAZAP2 Rabbit pAb
This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology FCHSD1 Rabbit pAb
Predicted to enable lipid binding activity. Predicted to be involved in neuromuscular synaptic transmission and positive regulation of actin filament polymerization. Predicted to be located in cell projection and perikaryon. Predicted to be active in neuromuscular junction and recycling endosome. Predicted to colocalize with cuticular plate.
ABclonal Technology LIN7C Rabbit pAb
Enables L27 domain binding activity and cytoskeletal protein binding activity. Involved in morphogenesis of an epithelial sheet. Located in cell-cell junction, cytoplasm, and plasma membrane. Part of MPP7-DLG1-LIN7 complex.
ABclonal Technology GABARAPL2 Rabbit pAb
Enables ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal protein catabolic process and protein localization to endoplasmic reticulum. Located in Golgi membrane and autophagosome membrane.
ABclonal Technology BMS1 Rabbit pAb
This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.
ABclonal Technology PDP1 Rabbit pAb
Pyruvate dehydrogenase (E1) is part of the pyruvate dehydrogenase complex (E1, E2, E3), with E1 activity regulated by phosphorylation and dephosphorylation. Pyruvate dehydrogenase kinases inactivate E1 by phosphorylating serine residues, while pyruvate dehydrogenase phosphatases activate E1 by dephosphorylation. The phosphatase is a heterodimer with catalytic and regulatory subunits. The catalytic subunit encoded by this gene is predominantly expressed in skeletal muscle and belongs to the protein phosphatase 2C (PP2C) superfamily. Located in the mitochondrial matrix, this enzyme, along with pyruvate dehydrogenase and kinases, regulates pyruvate metabolism. Mutations in this gene lead to pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced isoforms have been identified.
ABclonal Technology FABPI Rabbit pAb
The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis.
ABclonal Technology KIF7 Rabbit pAb
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
S2 Media 15x100mm Chameleon™ COLOREX™ Candida, 10/pack
Chameleon™ COLOREX™ Candida is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of Candida species. Test specimens include swabs from skin, throat, ears, and vaginal specimens, as well as sputum, urine, and stools. Samples should be tested in parallel to cultures on Sabouraud Dextrose Agar. Further identification, susceptibility testing, and epidemiological typing is needed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ Candida should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
ABclonal Technology UNC93B1 Rabbit pAb
This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis.
ABclonal Technology IL17RA Rabbit pAb
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
ABclonal Technology BATF3 Rabbit pAb
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.